AOD-9604

Potential Benefits of AOD-9604 Peptide

• AOD-9604 is a peptide fragment derived from the C-terminus of human growth hormone (HGH). Its structure encompasses amino acids 176-191, enabling it to stimulate lipolytic activity without the negative effects associated with full-length HGH molecules.
• Preclinical investigations have demonstrated significant reductions in body weight following administration of AOD-9604 in obese murine models. These findings underscore the peptide’s potential utility as an anti-obesity therapeutic agent [1].
• Unlike standard growth hormones, AOD-9604 does not stimulate cell proliferation, thus minimizing the risk of tumor formation. This feature elevates its safety profile for therapeutic applications [2].
• The peptide has demonstrated regenerative properties, enhancing cartilage repair in osteoarthritic models. This suggests potential applications within orthopedic medicine and the treatment of degenerative joint diseases [3].
• Within the broader context of biomedical research, AOD-9604 holds promise for the treatment of obesity, metabolic disorders, and possibly osteoarthritis. However, rigorous clinical trials are required to fully elucidate its therapeutic benefits and long-term safety profile [4].

References:

[1] https://pubmed.ncbi.nlm.nih.gov/11713213/

[2] https://pubmed.ncbi.nlm.nih.gov/11673763/

[3] https://pubmed.ncbi.nlm.nih.gov/26275694/

[4] https://clinicaltrials.gov/study/NCT00456131

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