Delta Sleep-Inducing Peptide (DSIP), a nonapeptide, is believed to function by modulating the body’s sleep patterns. The exact mechanism of DSIP’s function remains an active area of research, but it is believed to be involved in somnogenic and sedative actions, possibly through modulation of the GABAergic system or interaction with adenosine receptors. DSIP peptide is also thought to have a role in modulating the body’s response to stress and homeostasis of bodily processes.
The benefits of DSIP are primarily centered around its sleep-enhancing properties. Research has shown that DSIP can increase SWS (slow wave sleep) and REM sleep while reducing wakefulness. This makes it effective for cognitive functioning and potentially useful for treating sleep disorders such as insomnia. Additionally, DSIP has been found to exhibit anti-stress effects, possibly due to its ability to normalize the body’s response to stressors.
Moreover, DSIP has been observed to have an influence on endocrine systems. It has been associated with regulation of corticotropin-releasing hormone (CRH) levels, and thus, may have potential in managing diseases associated with CRH dysfunction.
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[1] https://pubmed.ncbi.nlm.nih.gov/6145137/
[2] https://www.mdpi.com/ 1420-3049/26/17/5173
[3] https://pubmed.ncbi.nlm.nih.gov/17957464/
[4] https://pubmed.ncbi.nlm.nih.gov/11214497/
[5] https://pubmed.ncbi.nlm.nih.gov/30281126/
[6] https://pubmed.ncbi.nlm.nih.gov/28462721/
[7] https://pubmed.ncbi.nlm.nih.gov/3909780/
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