Hexarelin

Potential Benefits of Hexarelin Peptide

• Cardiovascular Effects: Acute administration of Hexarelin has been observed to exert a short-lasting, positive inotropic effect, which is independent of growth hormone (GH) activity [1]. This suggests potential benefits for cardiovascular health.
• Bone Health: Hexarelin, a growth hormone–releasing peptide, has been shown to counteract bone loss in gonadectomized male rats [2]. This could imply a potential therapeutic role in conditions that cause bone loss.
• Cardioprotective Role: The peptide has been found to protect against myocardial infarction and can prevent the death of cardiomyocytes [3] and [4]. It’s also been found to attenuate abdominal aortic aneurysm formation [3].
• Endocrine and Metabolic Effects: Hexarelin has demonstrated significant endocrine and metabolic effects in obese Zucker rats [5]. This may suggest potential applications in metabolic disorder management.
• Potential Therapeutic Benefits: Hexarelin is a stable and effective Growth Hormone Secretagogue (GHS) that can potentially be used therapeutically [6]. Additionally, it has been researched for its possible utility in improving athletic performance and treating diseases that cause muscle wasting [7].
• Role in Diabetes and Associated Heart Diseases: Ghrelin and hexarelin, have been shown to exert GH-independent cardiovascular activity. They play physiological roles in the protection against diabetes and associated heart diseases [8].

References

[1] https://pubmed.ncbi.nlm.nih.gov/10342360/

[2] https://pubmed.ncbi.nlm.nih.gov/10512687/

[3] https://pubmed.ncbi.nlm.nih.gov/34856183/

[4] https://pubmed.ncbi.nlm.nih.gov/14615277/

[5] https://pubmed.ncbi.nlm.nih.gov/10974647/

[6] https://pubmed.ncbi.nlm.nih.gov/8762732/

[7] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC5638899/

[8] https://pubmed.ncbi.nlm.nih.gov/25645463/