AICAR

Description

AICAR Peptide Vial (AICA ribonucleotide) 50mg

This product is intended for research purposes only. To be used by trained professionals only.

AICAR peptide or referred to as 5-Aminoimidazole-4-carboxamide ribonucleotide. The AICAR peptide is a cell penetrable activator of AMPK (AMP-activated protein kinase) [1]. AMPK is a master regulatory authority of metabolic rate that is turned on in times of minimal power accessibility as well as functions to prevent anabolic metabolism. Inside the body, activation of AMPK with AICA ribonucleotide mimics that the body is working out and this sets off insulin-independent sugar uptake by muscular tissue cells.

Studies show that AICAR is important for boosting endurance as well as reducing stored fat. The AICAR peptide was shown to boost fat failure decades ago and also creates cells to move their fat stores into little organelles called mitochondria, where they are broken down but keep their energy [2]. Animal researches have actually revealed that AICAR can potently activate numerous metabolic genes to enhance workout endurance. Interestingly, the compound additionally increased the workout endurance in inactive animals.

Research suggests in animals, the compound has additionally been shown to minimize cells swelling and also advertise the healing of hurt and also broken cells. Human trials with AICA ribonucleotide have shown that it alters the way diabetics’ bodies react to sugar and thus improves their sugar control. Studies have shown that AICAR can act as a therapeutic approach to improve insulin action and prevent beta-cell dysfunction associated with type 2 diabetes, which may be achieved by activating AMPK. [3].

Furthermore, AICA ribonucleotide has been shown to protect against cardiac ischemic injury and enhance myocardial protection during heart coronary bypass surgery. It’s also been shown that AICAR peptide closely mimics the metabolic changes seen in people with muscle mass, even without any prior exercise [4]. AICAR also functions as an anti-inflammatory and minimizes inflammation by interfering with signalling molecules that cause cells to come to be triggered in mounting immune reaction. To conclude, AICAR works for tissue recovery, burning fat, promoting contraction and also for reducing swelling.

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References:

[1] https://www.ncbi.nlm.nih.gov/ pubmed/19853624

[2] https://www.nature.com/articles/ s41598-018-26102-3

[3] https://www.ncbi.nlm.nih.gov/ pubmed/15793229

[4] https://www.ncbi.nlm.nih.gov/ pubmed/11872652

Sequence: 5-Aminoimidazole-4-carboxamide ribonucleotide

Molecular Formula: C9H15N4O8P

Molecular Weight: 338.21 g/mol

Purity: 99%

Storage: Lyophilized peptides to be stored below -18°C

ALL CONTENT AND PRODUCT INFORMATION AVAILABLE ON THIS WEBSITE IS FOR EDUCATIONAL PURPOSES ONLY.

DISCLAIMER: These products are intended solely as a research chemical only. This classification allows for their use only for research development and laboratory studies. The information available on our Direct Peptides website: https://de.direct-peptides.com is provided for educational purposes only. These products are not for human or animal use or consumption in any manner. Handling of these products should be limited to suitably qualified professionals. They are not to be classified as a drug, food, cosmetic, or medicinal product and must not be mislabelled or used as such.

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