Decapeptide-12 (Topical)

Description

Decapeptide-12 200mg (Topical Peptide)

This product is intended for laboratory research purposes only. To be used by laboratory professionals only.

Decapeptide-12 topical is a synthetic peptide composed of twelve amino acids specifically engineered to inhibit the production of melanin. This makes it particularly effective for treating hyperpigmentation issues such as dark spots and uneven skin tone.

Decapeptide-12’s mechanism of action involves the inhibition of tyrosinase activity, which leads to a reduction in melanin synthesis and, consequently, a lightening of hyperpigmented areas. Research has indicated that Decapeptide-12 downregulates the expression of melanogenic enzymes, thereby contributing to its skin-brightening effects [2].

Clinical trials have showcased Decapeptide-12’s effectiveness in improving skin conditions such as melasma and post-inflammatory hyperpigmentation. Its capacity to accelerate the clearance of post-inflammatory hyperpigmentation has been particularly noted, making it a promising treatment for a wide range of skin types and conditions.

Hyperpigmentation, which includes conditions such as melasma, post-inflammatory hyperpigmentation, and solar lentigines, occurs due to the overproduction or uneven distribution of melanin in the skin. This can be triggered by a range of factors, including sun exposure, hormonal changes, and inflammation, negatively affecting the skin’s appearance and texture [1].

Recent clinical trials have demonstrated the potential of Decapeptide-12 topical peptide in the area of dermatology, particularly in its capacity to combat hyperpigmentation disorders. In one pivotal study, researchers discovered that a significant portion of the participants, 38.5%, experienced complete clearance of facial hyperpigmentation after being treated with Decapeptide-12 200mg.

Furthermore, an additional 30.7% of subjects observed their condition improve to only mild photodamage, highlighting the peptide’s efficacy in not only addressing severe cases but also in mitigating lesser degrees of skin damage. This research indicates that Decapeptide-12 topical peptide could be a versatile tool in the cosmetic and therapeutic management of hyperpigmentation [3].

Moreover, the safety profile of Decapeptide-12 200mg topical peptide has been thoroughly evaluated, with scientific research findings indicating minimal side effects, thereby affirming its suitability for ethnic skin, which can be more prone to adverse reactions with certain treatments. The peptide operates by inhibiting melanin synthesis, a crucial factor in the development of hyperpigmentation disorders such as melasma, solar lentigines, and even age-related wrinkles [3].

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References:

[1] Skin Pigmentation Types, Causes and Treatment-A Review. Molecules. 2023 Jun 18;28(12):4839 by Thawabteh AM, Jibreen A, Karaman D, Thawabteh A, Karaman R.

[2] Enhanced skin retention and permeation of a novel peptide via structural modification, chemical enhancement, and microneedles, International Journal of Pharmaceutics, Volume 606, 5 September 2021 by Jungen Chen, Junxing Bian et al.

[3] Open-label evaluation of the skin-brightening efficacy of a skin-brightening system using decapeptide-12. J Cosmet Laser Ther. 2012 Apr;14(2):117-21. by Kassim AT, Hussain M, Goldberg DJ.

Molecular formula: C65H90N18O17

Molecular weight: 1395.5 g/mol

ALL CONTENT AND PRODUCT INFORMATION AVAILABLE ON THIS WEBSITE IS FOR EDUCATIONAL PURPOSES ONLY.

DISCLAIMER: These products are intended solely as a research chemical only. This classification allows for their use only for research development and laboratory studies. The information available on our Direct Peptides website: https://de.direct-peptides.com is provided for educational purposes only. These products are not for human or animal use or consumption in any manner. Handling of these products should be limited to suitably qualified professionals. They are not to be classified as a drug, food, cosmetic, or medicinal product and must not be mislabelled or used as such.

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