GHK Basic (Topical)

Description

GHK Basic (Tripeptide-1) 50mg (Topical)

The GHK Basic also called tripeptide-1, a small yet potent molecule naturally synthesized in the human body, is comprised of three amino acids: glycine, histidine, and lysine. This tripeptide is particularly notable for its strong affinity for copper ions, with which it forms the GHK-Cu copper peptide complex. This complex is instrumental in orchestrating a myriad of biological processes crucial for maintaining health and vitality, including but not limited to wound healing, immune system responses, and the intricate process of tissue remodelling.

Research has found that GHK Basic tripeptide plays a pivotal role in the maintenance and enhancement of skin rejuvenation and health through its profound influence on collagen production [1]. Collagen, the most abundant protein in the human body, is essential for providing structure to the human skin, thus why it is the corner stone of many cosmetic products.

The beneficial effects of GHK is it’s ability to stimulate collagen synthesis not only aids in reinforcing the skin’s structural integrity but also in enhancing skin elasticity and firmness. This action is crucial for combating the visible signs of aging, such as sagging skin, fine lines and wrinkles. The tripeptide achieves this by promoting the production of glycosaminoglycans and decorin, components that support the collagen matrix and facilitate hydration retention within the skin. This can help with skin firmness and skin repair.

Clinical studies have demonstrated the effects of GHK tripeptide antioxidant capabilities, which play a crucial role in neutralizing harmful free radicals that are a by product of lipid peroxidation. This process is particularly damaging as it leads to the oxidation of fats in the body, which can contribute to various diseases and accelerate the aging process.

By effectively inactivating these damaging free radicals, GHK Basic not only safeguards the skin against oxidative stress but also enhances the body’s general defence against cellular damage [2]. This action is pivotal in maintaining the integrity of cells and preventing the deterioration of tissues, thereby supporting the body’s overall health and vitality.

Additionally, the effect of GHK Basic exhibits significant anti-inflammatory properties that are beneficial in mitigating inflammation across a range of organs, including the lungs, and in tissues that have sustained damage [3]. Inflammation is a natural response of the body to injury or infection, but when excessive, it can lead to chronic diseases and impair the healing process. GHK’s ability to modulate the release of iron from ferritin—a protein complex that stores iron in a non-toxic form—plays a vital role in its anti-inflammatory action.

By blocking the oxidation of low-density lipoproteins and providing protection against UV-light-induced skin damage, GHK Basic not only demonstrates a protective effect on the skin but also contributes to the reduction of systemic inflammation [2]. This dual action of GHK, combining antioxidant and anti-inflammatory effects, underscores its potential in therapeutic applications, particularly in conditions characterized by oxidative stress and inflammation.

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References:

[1] Stimulation of collagen synthesis in fibroblast cultures by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+, FEBS Letters Volume 238, Issue 2, 10 October 1988, Pages 343-346 by François-Xavier Maquart, Loren Pickart et al.

[2] New anti-RNS and -RCS products for cosmetic treatment. Int J Cosmet Sci. 2005 Oct;27(5):271-8. by Cebrián J, Messeguer A, Facino RM, García Antón JM.

[3] The tri-peptide GHK-Cu complex ameliorates lipopolysaccharide-induced acute lung injury in mice. Oncotarget. 2016 Sep 6;7(36):58405-58417. by Park JR, Lee H, Kim SI, Yang SR.

Molecular formula: C14H24N6O4

Molecular weight: 340.38

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DISCLAIMER: These products are intended solely as a research chemical only. This classification allows for their use only for research development and laboratory studies. The information available on our Direct Peptides website: https://de.direct-peptides.com is provided for educational purposes only. These products are not for human or animal use or consumption in any manner. Handling of these products should be limited to suitably qualified professionals. They are not to be classified as a drug, food, cosmetic, or medicinal product and must not be mislabelled or used as such.

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