Lipopeptide Topical Peptide

Description

Lipopeptide 200mg (Topical)

This product is intended for research purposes only. To be used by trained professionals only.

Lipopeptides, including key variants like Pal-GQPR and Palmitoyl Tetrapeptide-7/3, have emerged as ground breaking ingredients in the realm of skincare science. These compounds are unique because they are palmitoylated fragments, originating from immunoglobulin G (IgG). The process of palmitoylation, which attaches a lipid molecule to the peptide, significantly enhances their experimental capabilities. This chemical alteration not only increases their lipophilicity—making them more soluble in the lipid layers of the skin—but also improves their efficacy in penetrating the pores and acting within the skin’s cellular structure. This characteristic is crucial for their function in various dermatological treatments and skincare formulations which can give the best results [1].

Despite their potential and growing interest among researchers, it’s essential to understand that lipopeptides are primarily for in vitro testing for research use and not yet approved for direct human or animal consumption. Their promising role in enhancing skin repair and maintenance has, however, spotlighted them in the field of cosmetic science, leading to increased exploration of their applications in skincare product development including cleanser and night cream. Moreover topical peptides can have a significant impact on complexion including their protective effect from UV radiation.

The mechanism through which lipopeptides exert their significant role involves the stimulation of fibrillin-1 deposition. Fibrillin-1 is an essential glycoprotein and active ingredients that contributes to the skin’s elasticity and firmness, acting as a scaffold for elastin deposition according to research. This action, along with collagen, is crucial in reversing the signs of aging skin, where loss of elasticity is a predominant concern.

Furthermore, lipopeptides possess the ability to modulate inflammatory responses within the skin, notably through the reduction of IL-6 secretion. IL-6 is a cytokine implicated in inflammatory processes, and its reduction can mitigate inflammation-related skin damage, promoting a healthier skin environment. This attribute is especially beneficial in creating therapeutic strategies for managing skin disorders characterized by inflammation and redness of the skin cells [2].

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References:

[1] Evaluation of dermal extracellular matrix and epidermal–dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications, Journal of Cosmetic Dermatology, Volume 14, Issue 2, June 2015, Pages 152-160 by Philippe Mondon et al.

[2] Usage of Synthetic Peptides in Cosmetics for Sensitive Skin. Pharmaceuticals (Basel). 2021 Jul 21;14(8):702. by Resende DISP, Ferreira MS, Sousa-Lobo JM, Sousa E, Almeida IF.

Molecular formula: C38H68N6O8

Molecular weight: 736.9 g/mol

Sequence: Pal-Gly-Gln-Pro-Arg

ALL CONTENT AND PRODUCT INFORMATION AVAILABLE ON THIS WEBSITE IS FOR EDUCATIONAL PURPOSES ONLY.

DISCLAIMER: These products are intended solely as a research chemical only. This classification allows for their use only for research development and laboratory studies. The information available on our Direct Peptides website: https://de.direct-peptides.com is provided for educational purposes only. These products are not for human or animal use or consumption in any manner. Handling of these products should be limited to suitably qualified professionals. They are not to be classified as a drug, food, cosmetic, or medicinal product and must not be mislabelled or used as such.

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