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Humanin 10mg Pre Mixed

£52.49£141.72

Humanin is a short, bioactive peptide that has been connected to a variety of protective biological properties. It was initially found due to its potential to suppress neuronal cell death induced by the toxic effects of amyloid-beta in Alzheimer’s disease. Humanin may also play a function in cellular stress tolerance, inflammatory regulation, and lifespan extension, indicating potential therapeutic applications.

Pre Mixed Cartridge and Kit:
* 
1 x Cartridge (The cartridge is premixed with the peptide vial of your choice and Bacteriostatic Water)
* 1 x Peptide Cartridge Pen
* 1 x Pen Carry Case
* 3 x Pen Needle Tips

Single Mixed Cartridges (1,2 & 3) Come with:

* 1,2 or 3 x Cartridge (The cartridge is premixed with the peptide vial of your choice and Bacteriostatic Water)
* 3 x Pen Needle Tips
The single 1,2 & 3 cartridges do not come with a kit. Save 10% when buying 3 cartridges.

Buy 10 and get 10% Discount

Out of stock

Description

Buy Humanin Pre Mixed Peptide Pen 

This product is intended for research purposes only. To be used by trained professionals only.

Humanin is a mitochondrial-derived peptide (MDP) that has received a lot of attention in the scientific community because of its probable function in a variety of physiological processes. It was first found because of its neuroprotective benefits against Alzheimer’s disease-related insults, in which it reduces neuronal cell death caused by toxic amyloid-beta peptides [1].

According to research, Humanin pre mixed peptide is not only an anti-apoptotic peptide but also plays an important function in stress resistance [2]. This peptide appears to prevent apoptosis by interfering with Bax activation, a protein implicated in programmed cell death [3]. This Humanin characteristic may have far-reaching consequences in the treatment of apoptosis-related disorders.

Interestingly, research have found that Humanin levels are generally higher in a variety of animals and are associated with a longer lifespan and better health. This shows that Humanin may be involved in the regulation of ageing and health-related aspects. Humanin has also been found to interact with insulin-like growth factor-binding protein 3 (IGFBP-3), which affects cell survival and apoptosis [4].

Furthermore, new research has revealed an unexpected element of Humanin’s function: it appears to have a regulatory interaction with the formyl peptide receptor-like 1 and 2 proteins. Humanin N-formylated is known to decrease cAMP synthesis in specific cells [5]. This finding expands our knowledge of Humanin pre mixed peptide’s role in cellular signalling pathways.

According to one study on lung cancer, the circular RNA circNOL10 promotes SCML1-mediated transcriptional control of the Humanin polypeptide family [6]. This discovery sheds new light on Humanin pre mixed peptide’s possible therapeutic implications in cancer treatment. Humanin is a complex peptide with numerous biological roles. Its significance in neuroprotection, stress resistance, apoptosis regulation, and maybe cancer treatment make it an exciting area of study for the future.


References:

[1] https://www.sciencedirect.com/ science/article/abs/pii/S03043940 02001994

[2] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC3705736/

[3] https://www.nature.com/articles/ nature01627

[4] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC7343442/

[5] https://www.sciencedirect.com/ science/article/abs/pii/S0006291X 04020418

[6] https://onlinelibrary.wiley.com/ doi/full/10.1002/advs.201800654



Sequence:
Met-Ala-Pro-Arg-Gly-Phe-Ser-Cys-Leu-Leu-Leu-Leu-Thr-Ser-Glu-Ile-Asp-Leu-Pro-Val-Lys-Arg-Arg-Ala
Molecular Formula:
C121H205F3N34O34S2
Form:
Sterile Filtered White Lyophilized
Solubility:
Water Soluble
Purity:
>99.8%

Storage: Lyophilized peptides stored below -18°C.
Research use only. Not for human or animal consumption!

Humanin HPLC 2023 Certificates_DIRECT PEPTIDES

 

 

 

 

 

 

 

 


ALL CONTENT AND PRODUCT INFORMATION AVAILABLE ON THIS WEBSITE IS FOR EDUCATIONAL PURPOSES ONLY.

DISCLAIMER: These products are intended solely as a research chemical only. This classification allows for their use only for research development and laboratory studies. The information available on our Direct Peptides website: https://de.direct-peptides.com is provided for educational purposes only. These products are not for human or animal use or consumption in any manner. Handling of these products should be limited to suitably qualified professionals. They are not to be classified as a drug, food, cosmetic, or medicinal product and must not be mislabelled or used as such.


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