Tesamorelin

Description

Buy Tesamorelin Peptide vial

This product is intended for research purposes only. To be used by trained professionals only.

Tesamorelin is a synthetic peptide that mimics the effects of growth hormone-releasing hormone (GHRH), a naturally occurring hormone in the human body. It is primarily known for its ability to reduce belly fat in people living with HIV, a condition known as lipodystrophy. This synthetic analogue of GHRH works by binding to human growth hormone-releasing factor receptors, restoring the pulsatile release of growth hormones [1].

This mechanism helps regulate body composition, body fluids, muscle and bone growth, sugar and fat metabolism, and possibly heart function [2]. However, the benefits of Tesamorelin extend beyond the realm of HIV-associated lipodystrophy. The peptide has been recognized for its potential in weight loss and muscle growth, making it an area of interest within the sporting community.

Tesamorelin contains 44 amino acids, distinguishing it as one of the most popular peptides for muscle growth. It stimulates the pituitary gland, which is responsible for producing growth hormone. This stimulation promotes muscle growth and helps reduce body fat, contributing to overall physical enhancement [2].

In terms of weight management, in research Tesamorelin has been identified as one of the best peptides for weight loss. Originally used to treat HIV-associated lipodystrophy, the peptide has been found effective in reducing visceral adipose tissue, the fat stored deep in the belly surrounding vital organs.

Moreover, Tesamorelin’s influence on growth hormone release makes it a subject of interest in sports drug testing. Bioactive peptides like Tesamorelin, with an approximate molecular mass of 2–12 kDa, have been used to manipulate several potential performance-enhancing effects. Consequently, there are ongoing efforts to develop efficient test methods for detecting such peptides [3].

In the field of peptide and protein synthesis, Tesamorelin has also been used as a model for developing novel technologies. The peptide’s complex structure, modified with an N-terminal trans 2-hexenoyl moiety for protection1, poses unique challenges in synthetic methods that can help advance the broader field of peptide therapeutics.

References:

[1] https://www.thelancet.com/ journals/lanhiv/article/PIIS2352-3018(19)30331-5/fulltext

[2] https://journals.lww.com/jpbs/ Fulltext/2011/03020/Tesamorelin __A_hope_for_ART_induced_ lipodystrophy.28.aspx

[3] https://analyticalsciencejournals. onlinelibrary.wiley.com/doi/abs/ 10.1002/dta.1868

Molecular Formula: C221H366N72O67S

Molecular Weight: 5135.77

Sequence: trans-hexenoyl-acid-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn- Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-LeuGln-Asp-Ile-Met-Ser-Arg-Gln- Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly-Ala-Arg-Ala-Arg-Leu-NH2

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DISCLAIMER: These products are intended solely as a research chemical only. This classification allows for their use only for research development and laboratory studies. The information available on our Direct Peptides website: https://de.direct-peptides.com is provided for educational purposes only. These products are not for human or animal use or consumption in any manner. Handling of these products should be limited to suitably qualified professionals. They are not to be classified as a drug, food, cosmetic, or medicinal product and must not be mislabelled or used as such.

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